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What Affects the Rate of Reaction? Essay title: What Affects the Rate of Reaction? What affects the Rate of Reaction? The reaction I will use for this test is: 2HCl(aq) + CaCO3(s) CaCl2(aq) + CO2(g) + H2O(l) The possible variables for this experiment are the concentration of acid; the surface area of the solid reactant,.