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Synthesis of 2,4-Dnp: Nucleophilic Aromatic Substitution Essay Preview: Synthesis of 2,4-Dnp: Nucleophilic Aromatic Substitution Report this essay Exercise 1: Synthesis of 2,4-DNP: Nucleophilic Aromatic Substitution (SnAr)INTRODUCTION Nucleophilic Aromatic Substitution involves two steps and it has a resonance-stabilized intermediate, called a Meisenheimer complex. This intermediate exhibits a negative charge that is resonance stabilized throughout the ring. Nucleophilic.