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Osmoregulation Lab – Observing Osmoregulation Observing Osmoregulation Introduction: The main function of the kidney is to regulate the osmolality of the body’s fluids. In this lab, students observe osmoregulation by testing urine samples. The students divide into three groups. Each group drinks 800 ml water, 800 ml Gatorade, or 7 grams of NaCl with 80.